{"url_path":"/sec/obio/10-q/2026/item-6","section_key":"item-6","section_title":"Item 6 Exhibits.","topic":"sec","document":{"doc_type":"10-Q","doc_date":"2026-05-12","source_url":"https://www.sec.gov/Archives/edgar/data/1814114/0001104659-26-059382-index.html","accession_number":"0001104659-26-059382","cik":"0001814114","ticker":"OBIO","issuer_name":"Orchestra BioMed Holdings, Inc.","edgar_url":"https://www.sec.gov/Archives/edgar/data/1814114/0001104659-26-059382-index.html","primary_entity_key":"0001814114","primary_entity_name":"Orchestra BioMed Holdings, Inc."},"word_count":540,"has_tables":true,"body_markdown":"Item 6. Exhibits.\n\n**Exhibit**\n\n**  ​ ​ ​**\n\n**Description**\n\n3.1\n\n​\n\n[Certificate of Incorporation of Orchestra BioMed Holdings, Inc. (incorporated by reference to Exhibit 3.1 to the Current Report on Form 8-K filed with the SEC on January 31, 2023).](https://www.sec.gov/Archives/edgar/data/1814114/000121390023006448/ea172444ex3-1_orchestra.htm)\n\n3.2\n\n​\n\n[Certificate of Designation of Series A Convertible Preferred Stock, dated November 6, 2025 (incorporated by reference to Exhibit 3.2 to the Company’s Quarterly Report on Form 10-Q filed with the SEC on November 10, 2025)](https://www.sec.gov/Archives/edgar/data/1814114/000110465925109128/obio-20250930xex3d2.htm)\n\n3.3\n\n​\n\n[Amended and Restated Bylaws of Orchestra BioMed Holdings, Inc. (incorporated by reference to Exhibit 3.2 to the Quarterly Report on Form 10-Q filed with the SEC on August 12, 2024).](https://www.sec.gov/Archives/edgar/data/1814114/000155837024011899/obio-20240630xex3d2.htm)\n\n10.1+˄†\n\n​\n\n[First Amendment to Loan and Security Agreement by and among the Company and certain of its subsidiaries, the lenders named therein and Hercules Capital, Inc., dated as of December 30, 2024.](obio-20260331xex10d1.htm)\n\n10.2+˄†\n\n​\n\n[Third Amendment to Loan and Security Agreement by and among the Company and certain of its subsidiaries, the lenders named therein and Hercules Capital, Inc., dated as of April 6, 2026.](obio-20260331xex10d2.htm)\n\n31.1+\n\n​\n\n[Certification of Chief Executive Officer, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](obio-20260331xex31d1.htm)\n\n31.2+\n\n​\n\n[Certification of Chief Financial Officer, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](obio-20260331xex31d2.htm)\n\n32.1*\n\n​\n\n[Certification of Chief Executive Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.](obio-20260331xex32d1.htm)\n\n32.2*\n\n​\n\n[Certification of Chief Financial Officer, pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.](obio-20260331xex32d2.htm)\n\n101.INS\n\n​\n\nInline XBRL Instance Document.\n\n101.SCH\n\n​\n\nInline XBRL Taxonomy Extension Schema Document.\n\n101.CAL\n\n​\n\nInline XBRL Taxonomy Extension Calculation Linkbase Document.\n\n101.DEF\n\n​\n\nInline XBRL Taxonomy Extension Definition Linkbase Document.\n\n101.LAB\n\n​\n\nInline XBRL Taxonomy Extension Label Linkbase Document.\n\n101.PRE\n\n​\n\nInline XBRL Taxonomy Extension Presentation Linkbase Document.\n\n104\n\n​\n\nCover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101).\n\n+Filed herewith.\n\n#     Indicates a management contract or compensatory plan.\n\n*\n\nFurnished herewith. This exhibit shall not be deemed “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that Section. Such exhibit shall not be deemed incorporated into any filing under the Securities Act or the Exchange Act.\n\n˄\n\nCertain identified information has been omitted pursuant to Item 601(b)(10) of Regulation S-K because such information is both (i) not material and (ii) information that the Registrant treats as private or confidential. The Registrant hereby undertakes to furnish supplemental copies of the unredacted exhibit upon request by the SEC.\n\n†\n\nCertain of the exhibits and schedules to this Exhibit have been omitted in accordance with Regulation S-K Item 601. The Registrant agrees to furnish a copy of all omitted exhibits and schedules to the SEC upon its request.\n\n​\n\n42\n\n[Table of Contents](#TOC)\n\nSIGNATURES\n\nPursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.\n\n​\n\n​\n\n​\n\nORCHESTRA BIOMED HOLDINGS, INC.\n\n​\n\n​\n\nDated: May 12, 2026\n\n/s/ Andrew Taylor\n\n​\n\nAndrew Taylor\n\n​\n\nChief Financial Officer\n\n​\n\n(Principal Financial Officer)\n\n​\n\n​\n\n​\n\n​\n\n​\n\n43"}