{"url_path":"/sec/sclx/10-q/2026/item-6","section_key":"item-6","section_title":"Item 6 Exhibits.","topic":"sec","document":{"doc_type":"10-Q","doc_date":"2026-05-20","source_url":"https://www.sec.gov/Archives/edgar/data/1820190/0001193125-26-232857-index.html","accession_number":"0001193125-26-232857","cik":"0001820190","ticker":"SCLX","issuer_name":"Scilex Holding Co","edgar_url":"https://www.sec.gov/Archives/edgar/data/1820190/0001193125-26-232857-index.html","primary_entity_key":"0001820190","primary_entity_name":"Scilex Holding Co"},"word_count":1900,"has_tables":true,"body_markdown":"Item 6. Exhibits.\n\n \n\nExhibit\n\nNumber\n\nDescription\n\n   2.1#\n\n[Agreement and Plan of Merger, dated as of March 18, 2019, by and among Scilex Holding Company, Sigma Merger Sub, Inc., Semnur Pharmaceuticals, Inc., Fortis Advisors LLC, solely as the representative of the Equityholders and, solely with respect to Section 1.8(a), Section 3.11 and Article X, Sorrento Therapeutics, Inc. (incorporated by reference to Exhibit 2.1 of Amendment No. 1 of Vickers’s Form S-4 (File No. 333-264941), filed with the SEC on June 27, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000110465922074469/vcka-20220331xex2d1.htm)\n\n   2.2\n\n[Amendment No. 1 to Agreement and Plan of Merger, dated as of August 7, 2019, by and among Semnur Pharmaceuticals, Inc., Scilex Holding Company, Sigma Merger Sub, Inc., Fortis Advisors, LLC, solely as the representative of the Equityholders and, solely with respect to Section 1.8(a), 3.11 and Article X of the Agreement and Plan of Merger, Sorrento Therapeutics, Inc. (incorporated by reference to Exhibit 2.2 of Amendment No. 1 of Vickers’s Form S-4 (File No. 333-264941), filed with the SEC on October June 27, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000110465922074469/vcka-20220331xex2d2.htm)\n\n   2.3#\n\n[Bill of Sale and Assignment and Assumption Agreement, dated May 12, 2022, by and between Scilex Holding Company and Sorrento Therapeutics, Inc. (incorporated by reference to Exhibit 2.3 of Amendment No. 1 of Vickers’s Form S-4 (File No. 333-264941), filed with the SEC on June 27, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000110465922074469/vcka-20220331xex2d3.htm)\n\n   2.4^#\n\n[Asset Purchase Agreement, dated April 23, 2021, between Sorrento Therapeutics, Inc. and Aardvark Therapeutics, Inc., as assumed by Scilex Holding Company on May 12, 2022, pursuant to the Bill of Sale and Assignment and Assumption Agreement, dated as of such date, by and between Scilex Holding Company and Sorrento Therapeutics, Inc. (incorporated by reference to Exhibit 2.4 of Amendment No. 1 of Vickers’s Form S-4 (File No. 333-264941), filed with the SEC on June 27, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000110465922074469/vcka-20220331xex2d4.htm)\n\n   2.5#\n\n[Agreement and Plan of Merger, dated as of March 17, 2022, by and among Vickers Vantage Corp. I, Vickers Merger Sub, Inc. and Scilex Holding Company (incorporated by reference to Exhibit 2.1 of Vickers’s Current Report on Form 8-K (File No. 001-39852), filed with the SEC on March 21, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000121390022013697/ea157097ex2-1_vickers1.htm)\n\n   2.6#\n\n[Amendment No. 1 to Agreement and Plan of Merger, dated as of September 12, 2022, by and among Vickers Vantage Corp. I, Vickers Merger Sub, Inc. and Scilex Holding Company (incorporated by reference to Exhibit 2.1 of Vickers’s Current Report on Form 8-K (File No. 001-39852), filed with the SEC on September 14, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000110465922099785/tm2225830d1_ex2-1.htm)\n\n   2.7#\n\n[Agreement and Plan of Merger, dated as of August 30, 2024, by and among Denali Capital Acquisition Corp., Denali Merger Sub Inc. and Semnur Pharmaceuticals, Inc. (incorporated by reference to Exhibit 2.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on September 3, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524211651/d852041dex21.htm)\n\n \n\n \n\n   2.8\n\n[Amendment No. 1 to Agreement and Plan of Merger, dated as of April 16, 2025, by and among Denali Capital Acquisition Corp., Denali Merger Sub Inc. and Semnur Pharmaceuticals, Inc. (incorporated by reference to Exhibit 2.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on April 21, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000095017025056022/sclx-ex2_1.htm)\n\n \n\n \n\n   2.9\n\n[Amendment No. 2 to Agreement and Plan of Merger, dated as of July 22, 2025, by and among Denali CapitalAcquisition Corp., Denali Merger Sub Inc. and Semnur Pharmaceuticals, Inc. (incorporated by reference to Exhibit2.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on July 23, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525162969/d21770dex21.htm)\n\n \n\n \n\n   3.1\n\n[Restated Certificate of Incorporation of Scilex Holding Company (incorporated by reference to Exhibit 3.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on November 17, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000119312522287783/d374632dex31.htm)\n\n \n\n \n\n   3.2\n\n[Certificate of Amendment to the Restated Certificate of Incorporation of Scilex Holding Company, filed with the Secretary of State of the State of Delaware on April 14, 2025 (incorporated by reference to Exhibit 3.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on April 15, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525080856/d943368dex31.htm)\n\n   3.3\n\n[Certificate of Designations of Scilex Holding Company (incorporated by reference to Exhibit 3.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on November 17, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000119312522287783/d374632dex32.htm)\n\n \n\n \n\n   3.4\n\n[Certificate of Designation of Preferences, Rights and Limitations of Series 1 Mandatory Exchangeable Preferred Stock of Scilex Holding Company (incorporated by reference to Exhibit 3.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on October 28, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000095017024117557/sclx-ex3_1.htm)\n\n \n\n \n\n   3.5\n\n[Certificate of Elimination of Series 1 Mandatory Exchangeable Preferred Stock of Scilex Holding Company (incorporated by reference to Exhibit 3.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on February 3, 2026).](https://www.sec.gov/Archives/edgar/data/1820190/000119312526035833/d79855dex31.htm)\n\n \n\n \n\n \n\n98\n\n \n\nExhibit\n\nNumber\n\nDescription\n\n   3.6\n\n[Bylaws of Scilex Holding Company (incorporated by reference to Exhibit 3.3 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on November 17, 2022).](https://www.sec.gov/Archives/edgar/data/1820190/000119312522287783/d374632dex33.htm)\n\n   4.1\n\n[Warrant Agreement, dated as of January 6, 2021, by and between Vickers Vantage Corp. I and Continental Stock Transfer & Trust Company (incorporated by reference to Exhibit 4.1 of Vickers’s Current Report on Form 8-K (File No. 001-39852), filed with the SEC on January 11, 2021).](https://www.sec.gov/Archives/edgar/data/1820190/000121390021001411/ea133037ex4-1_vickers1.htm)\n\n \n\n \n\n   4.2\n\n[Specimen Warrant Certificate of Scilex Holding Company (f/k/a Vickers Vantage Corp. I) (incorporated by reference to Exhibit 4.3 of Vickers’s Form S-1 (File No. 333-251352), filed with the SEC on December 15, 2020).](https://www.sec.gov/Archives/edgar/data/1820190/000121390020042745/fs12020ex4-3_vickers1.htm)\n\n \n\n \n\n   4.3\n\n[Senior Secured Promissory Note issued to Oramed Pharmaceuticals Inc. on September 21, 2023 (incorporated by reference to Exhibit 4.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on September 26, 2023).](https://www.sec.gov/Archives/edgar/data/1820190/000119312523242508/d537034dex41.htm)\n\n \n\n \n\n   4.4\n\n[Form of Scilex Holding Company Warrant to Purchase Common Stock (incorporated by reference to Exhibit 4.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on September 26, 2023).](https://www.sec.gov/Archives/edgar/data/1820190/000119312523242508/d537034dex42.htm)\n\n \n\n \n\n   4.5\n\n[Form of Common Warrant (incorporated by reference to Exhibit 4.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on March 5, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524059255/d772929dex41.htm)\n\n \n\n \n\n   4.6\n\n[Form of Representative Warrant (incorporated by reference to Exhibit 4.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on March 5, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524059255/d772929dex42.htm)\n\n \n\n \n\n   4.7\n\n[Form of Common Warrant (incorporated by reference to Exhibit 4.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on April 25, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524159926/d55926dex41.htm)\n\n \n\n \n\n   4.8\n\n[Form of Placement Agent Warrant (incorporated by reference to Exhibit 4.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on April 25, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524159926/d55926dex41.htm)\n\n \n\n   4.9\n\n[Warrant to Purchase Common Stock, issued to FSF 33433 LLC on June 18, 2024 (incorporated by reference to Exhibit 4.8 of our Registration Statement on Form S-3 (File No. 333-280882), filed with the SEC on July 18, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524181039/d699096dex48.htm)\n\n \n\n \n\n   4.10\n\n[Form of Tranche B Senior Secured Convertible Note issued by Scilex Holding Company. (incorporated by reference to Exhibit 4.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on October 8, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524234244/d853982dex41.htm)\n\n \n\n \n\n   4.11\n\n[Form of Warrant to Purchase Common Stock issued by Scilex Holding Company. (incorporated by reference to Exhibit 4.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on October 8, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524234244/d853982dex42.htm)\n\n \n\n \n\n   4.12\n\n[Form of Placement Agent Warrant issued by Scilex Holding Company (incorporated by reference to Exhibit 4.3 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on October 8, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524234244/d853982dex43.htm)\n\n \n\n \n\n   4.13\n\n[Form of Pre-Funded Warrant issued by Scilex Holding Company (incorporated by reference to Exhibit 4.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on December 13, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524278311/d836578dex41.htm)\n\n \n\n \n\n   4.14\n\n[Form of Common Warrant issued by Scilex Holding Company (incorporated by reference to Exhibit 4.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on December 13, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524278311/d836578dex42.htm)\n\n \n\n \n\n   4.15\n\n[Form of StockBlock Warrant issued by Scilex Holding Company (incorporated by reference to Exhibit 4.3 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on December 13, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524278311/d836578dex43.htm)\n\n \n\n \n\n   4.16\n\n[Form of New Tranche B Warrant (incorporated by reference to Exhibit 10.6 of our Current Report on Form 8-K(File No. 001-39852), filed with the SEC on July 23, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525162938/d87162dex106.htm)\n\n \n\n \n\n   4.17\n\n[Amendment No. 1 to Common Stock Purchase Warrant, dated December 11, 2024, between Scilex Holding Company and the investor named therein (incorporated by reference to Exhibit 4.4 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on December 13, 2024).](https://www.sec.gov/Archives/edgar/data/1820190/000119312524278311/d836578dex44.htm)\n\n \n\n \n\n   4.18\n\n \n\n[Form of September 2025 Warrant (incorporated by reference to Exhibit 10.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on October 1, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525226992/sclx-ex10_2.htm)\n\n \n\n \n\n   4.19\n\n[Form of November 2025 Investor Warrant (incorporated by reference to Exhibit 10.2 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on November 24, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525293861/d54587dex102.htm)\n\n \n\n \n\n \n\n99\n\n \n\nExhibit\n\nNumber\n\nDescription\n\n   4.20\n\n[Form of November 2025 Placement Agent Warrant (incorporated by reference to Exhibit 10.3 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on November 24, 2025).](https://www.sec.gov/Archives/edgar/data/1820190/000119312525293861/d54587dex103.htm)\n\n \n\n \n\n   4.21+\n\n[Convertible Promissory Note, dated January 29, 2026, issued by Quantum Scan Holdings, Inc. in favor of Scilex Holding Company.](sclx-ex4_21.htm)\n\n \n\n \n\n   10.1\n\n \n\n[Warrant Agreement, dated as of February 19, 2026, by and between the Company and Oramed Pharmaceuticals Inc. (incorporated by reference to Exhibit 10.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on February 20, 2026).](https://www.sec.gov/Archives/edgar/data/1820190/000119312526061371/sclx-ex10_1.htm)\n\n \n\n \n\n10.2+\n\n[Common Stock Purchase Agreement, dated January 29, 2026, by and between Scilex Holding Company and Quantum Scan Holding, Inc.](sclx-ex10_2.htm)\n\n \n\n \n\n   10.3+\n\n[Stock Acquisition Agreement, dated May 4, 2026, by and between the Company and ACEA Therapeutics, Inc. (incorporated by reference to Exhibit 10.1 of our Current Report on Form 8-K (File No. 001-39852), filed with the SEC on May 5, 2026).](sclx-ex10_3.htm)\n\n \n\n \n\n   31.1+\n\n[Certification of Henry Ji, Ph.D., Principal Executive Officer, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](sclx-ex31_1.htm)\n\n \n\n \n\n   31.2+\n\n[Certification of Stephen Ma, Principal Financial Officer, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.](sclx-ex31_2.htm)\n\n \n\n \n\n   32.1++\n\n[Certification of Henry Ji, Ph.D., Principal Executive Officer, and Stephen Ma, Principal Financial Officer, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.](sclx-ex32_1.htm)\n\n101.INS+\n\nInline XBRL Instance Document.\n\n101.SCH+\n\nInline XBRL Taxonomy Extension Schema Document.\n\n101.CAL+\n\nInline XBRL Taxonomy Extension Calculation Linkbase Document.\n\n101.DEF+\n\nInline XBRL Taxonomy Extension Definition Linkbase Document.\n\n101.LAB+\n\nInline XBRL Taxonomy Extension Labels Linkbase Document.\n\n101.PRE+\n\nInline XBRL Taxonomy Extension Presentation Linkbase Document.\n\n104+\n\nCover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101).\n\n \n\n+ Filed herewith.\n\n++ Furnished herewith.\n\n^ Certain identified information has been omitted pursuant to Item 601(b)(10) of Regulation S-K because such information is both (i) not material and (ii) information that the Registrant treats as private or confidential. The Registrant hereby undertakes to furnish supplemental copies of the unredacted exhibit upon request by the SEC.\n\n# Certain of the exhibits and schedules to this Exhibit have been omitted in accordance with Regulation S-K Item 601. The Registrant agrees to furnish a copy of all omitted exhibits and schedules to the SEC upon its request.\n\n \n\n \n\n \n\n \n\n \n\n100\n\n \n\nSIGNATURES\n\n \n\nPursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.\n\nMay 20 2026\n\nScilex Holding Company\n\nBy:\n\n/s/ Henry Ji, Ph.D.\n\nHenry Ji, Ph.D.\nChief Executive Officer and President\n\n(Principal Executive Officer)\n\nMay 20, 2026\n\n \n\nBy:\n\n/s/ Stephen Ma\n\nStephen Ma\nChief Financial Officer\n\n(Principal Financial Officer)\n\n \n\n \n\n101"}