# Possession, Use, and Transfer of Select Agents and Toxins; Regulation of an Attenuated Vaccine Strain of Venezuelan Equine Encephalitis Virus as a Select Agent
> **Animal and Plant Health Inspection Service** · Regulatory determination. · Published 2022-09-01 · Effective 2022-09-01 · 87 FR 53647
## Document
- **Document number:** 2022-18990
- **Category:** plant-animal-health
- **Sub-agency:** Animal and Plant Health Inspection Service
- **Federal Register citation:** 87 FR 53647
- **CFR reference:** 9 CFR 121
- **Publication date:** 2022-09-01
- **Effective date:** 2022-09-01
- **USDA docket:** Docket No. APHIS-2022-0034
## Abstract

We are notifying the public that the Animal and Plant Health Inspection Service (APHIS) has determined that the modified Venezuelan equine encephalitis virus (VEEV) strain TC-83(A3G), which is a modification to the attenuated strain VEEV TC-83, has demonstrated increased pathogenicity and lethality and that the strain has the potential to pose a severe threat to animal health or animal products. We are advising the public that VEEV strain TC-83(A3G) is therefore a select agent and subject to APHIS' select agent and toxin regulations.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2022/09/01/2022-18990/possession-use-and-transfer-of-select-agents-and-toxins-regulation-of-an-attenuated-vaccine-strain)
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