# Viruses, Serums, Toxins, and Analogous Products; Standard Requirements for Live Vaccines
> **Animal and Plant Health Inspection Service** · Final rule. · Published 2007-12-21 · Effective 2008-01-22 · 72 FR 72563
## Document
- **Document number:** E7-24649
- **Category:** meat-poultry
- **Sub-agency:** Animal and Plant Health Inspection Service
- **Federal Register citation:** 72 FR 72563
- **CFR reference:** 9 CFR 113
- **Publication date:** 2007-12-21
- **Effective date:** 2008-01-22
- **USDA docket:** Docket No. APHIS-2006-0079
## Abstract

We are amending the Virus-Serum-Toxin Act regulations for certain live bacterial and viral vaccines by removing the requirement to retest the Master Seeds for immunogenicity 3 years after the initial qualifying immunogenicity test. In addition, we are amending the requirement concerning mouse safety tests prescribed for a biological product recommended for animals other than poultry. These changes update the standard requirements by eliminating unnecessary testing of Master Seed bacteria and viruses and other forms of bulk or completed biological product.

## Source
- [Federal Register document](https://www.federalregister.gov/documents/2007/12/21/E7-24649/viruses-serums-toxins-and-analogous-products-standard-requirements-for-live-vaccines)
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