The contact owned a 2020 Honda Pilot. The contact stated that while her son was driving approximately 55 mph the brake pedal was applied however failed to respond the vehicle crashed into a fence. The wheel assembly detached. There were no warning indicator lights illuminated. The driver sustain muscle injuries and medical attention was provided. A police report was filed. The air bags deployed. There was no reported fire. The vehicle was towed to an independent mechanic. The local dealer was not contacted. The vehicle was not diagnosed or repaired. The manufacturer was notified however, no further assistance was provided. The approximate failure mileage was 18,000. The insurance company deemed the vehicle a total loss.