The contact owned a 2017 Mercedes-Benz E300W. The contact stated while driving approximately 55mph when the contact heard a loud noise coming from the vehicle causing him to lose control of the vehicle and crash into another vehicle. The contact stated the crash avoidance system had failed to activate. The contact stated no warning lights were illuminated. The contact sustained arm bruises but did not seek medical treatment. The other vehicle contained 2 people but the contact does not know what injuries they had sustained. The vehicle was towed to a tow lot and a police report was filed. The vehicle was destroyed. The manufacturer was not informed of the failure. The failure mileage was approximately 47,000.