While traveling around 40 mph on a roadway another vehicle ran a stop sign approximately 2 feet in front of my vehicle. This vehicle came onto the roadway from a side road at a sustained speed with no braking. I swerved to avoid impact and went over an embankment. The vehicle sustained extensive damage to the front and underneath. It is a total loss. The airbags did not deploy during the accident. There were also serious injuries to the driver and passenger. The driver sustained a broken neck in 4 places. The passenger sustained massive hematomas, a fractured arm, and 7 fractured ribs in the chest and separated sternum. There were no warning lights or messages displayed. An inspection has not been performed on the airbag system. The vehicle is currently located at the insurance company's salvage yard.