While driving with the cruise control set at 52mph, I was coming to a known left curve with a stop sign four way intersection that follows it (I drive this route at least 50% of the time whenever leaving my home). I hit the 'Cancel' button to stop the cruise control as I came to the curve, and there was no response. I hit the brakes and again there was no response. At that point I prepared for a wreck because I knew the curve was tight, followed by that intersection's stop sign, and I was almost upon the curve. Continuing to try to apply brakes and getting no response, I could not hold the curve of the road and left the roadway to the right side. I narrowly avoided a lightpole, and then I was finally at the ditch of the crossroad already mentioned. The truck struck the ditch embankment facing me and likely launched airborn at that point, going across the first lane of the crossroad. After about the width of that lane, it appears that's when the front suspension landed, gouging the asphalt and deploying the airbag on me at that point. This seems to be when the braking system finally responded as I started to slow down some, as it bounced and jerked across the remaining lanes, leaving skid marks on that part of the road. I steered it between two signs on the far side, still barely under control but it finally slowing down into the 20s or so, where I had control and brought it to a stop. The vehicle had no known issues or ODBII scan codes prior to this incident. *After the incid