Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia

NCT00003619 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

OTHER

Sponsor class

Conditions

Chronic Myeloproliferative Disorders
Leukemia
Myelodysplastic Syndromes
Thrombocytopenia

Interventions

BIOLOGICAL: filgrastim
DIETARY_SUPPLEMENT: vitamin E
DRUG: busulfan
DRUG: cytarabine
DRUG: etoposide
DRUG: fludarabine phosphate
DRUG: isotretinoin
DRUG: topotecan hydrochloride
PROCEDURE: bone marrow ablation with stem cell support
PROCEDURE: peripheral blood stem cell transplantation

Sponsor

Drexel University College of Medicine