Total-Body Irradiation Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Severe Combined Immunodeficiency Undergoing Donor Bone Marrow Transplant

NCT00008450 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

6

Enrollment

OTHER

Sponsor class

Conditions

Adenosine Deaminase Deficiency
Autosomal Recessive Disorder
Immune System Disorder
Purine-Nucleoside Phosphorylase Deficiency
Severe Combined Immunodeficiency
Severe Combined Immunodeficiency With Absence of T and B Cells
X-Linked Severe Combined Immunodeficiency

Interventions

PROCEDURE: Allogeneic Bone Marrow Transplantation
DRUG: Cyclosporine
OTHER: Laboratory Biomarker Analysis
DRUG: Mycophenolate Mofetil
PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
RADIATION: Total-Body Irradiation

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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