Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Conditions

• Adult Acute Lymphoblastic Leukemia in Remission

Interventions

• DRUG: imatinib mesylate
• DRUG: methotrexate
• DRUG: vincristine sulfate
• DRUG: leucovorin calcium
• PROCEDURE: peripheral blood stem cell transplantation
• PROCEDURE: autologous hematopoietic stem cell transplantation
• PROCEDURE: allogeneic hematopoietic stem cell transplantation
• RADIATION: total-body irradiation
• DRUG: tacrolimus
• BIOLOGICAL: filgrastim
• DRUG: etoposide
• DRUG: cyclophosphamide
• DRUG: cytarabine
• OTHER: laboratory biomarker analysis

Sponsor

National Cancer Institute (NCI)