Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
Conditions
- Childhood Burkitt Lymphoma
- Childhood Diffuse Large Cell Lymphoma
- Childhood Immunoblastic Large Cell Lymphoma
- Stage I Childhood Large Cell Lymphoma
- Stage I Childhood Small Noncleaved Cell Lymphoma
- Stage II Childhood Large Cell Lymphoma
- Stage II Childhood Small Noncleaved Cell Lymphoma
- Stage III Childhood Large Cell Lymphoma
- Stage III Childhood Small Noncleaved Cell Lymphoma
- Stage IV Childhood Large Cell Lymphoma
- Stage IV Childhood Small Noncleaved Cell Lymphoma
- Untreated Childhood Acute Lymphoblastic Leukemia
Interventions
- DRUG: doxorubicin hydrochloride
- DRUG: cyclophosphamide
- DRUG: methotrexate
- DRUG: rasburicase
- DRUG: leucovorin calcium
- DRUG: prednisone
- DRUG: methylprednisolone
- BIOLOGICAL: filgrastim
- BIOLOGICAL: rituximab
- DRUG: cytarabine
- DRUG: etoposide
- DRUG: vincristine sulfate
- DRUG: hydrocortisone sodium succinate
- OTHER: laboratory biomarker analysis
Sponsor
Children's Oncology Group
Collaborators