Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases

NCT00376519 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

3

Enrollment

OTHER

Sponsor class

Stopped Slow accrual

Conditions

Graft Versus Host Disease
Leukemia
Lymphoma
Multiple Myeloma and Plasma Cell Neoplasm
Myelodysplastic Syndromes
Secondary Myelofibrosis

Interventions

DRUG: cyclophosphamide
DRUG: cyclosporine
DRUG: fludarabine phosphate
DRUG: mycophenolate mofetil
PROCEDURE: Treg cell infusion
PROCEDURE: umbilical cord blood transplantation
RADIATION: total-body irradiation

Sponsor

Masonic Cancer Center, University of Minnesota