Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

NCT00544778 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

7

Enrollment

OTHER

Sponsor class

Stopped The study was terminated prematurely due to withdrawal of support by the sponsor.

Conditions

Sarcoma

Interventions

BIOLOGICAL: filgrastim
DRUG: dexrazoxane hydrochloride
DRUG: doxorubicin hydrochloride
DRUG: ifosfamide
DRUG: irinotecan hydrochloride
GENETIC: protein expression analysis
OTHER: immunoenzyme technique
PROCEDURE: adjuvant therapy
PROCEDURE: conventional surgery
PROCEDURE: neoadjuvant therapy
RADIATION: radiation therapy

Sponsor

City of Hope Medical Center

Collaborators

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