Cetuximab, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Head and Neck Cancer That Cannot Be Removed By Surgery

NCT00646659 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

47

Enrollment

NETWORK

Sponsor class

Stopped Recruitment was suspended prematurely for safety concerns and closed after IDMC review

Conditions

Head and Neck Cancer

Interventions

BIOLOGICAL: cetuximab
DRUG: carboplatin
DRUG: cisplatin
DRUG: docetaxel
DRUG: fluorouracil
GENETIC: fluorescence in situ hybridization
GENETIC: molecular genetic technique
GENETIC: reverse transcriptase-polymerase chain reaction
OTHER: immunoenzyme technique
OTHER: immunohistochemistry staining method
OTHER: laboratory biomarker analysis
PROCEDURE: biopsy
RADIATION: 3-dimensional conformal radiation therapy
RADIATION: intensity-modulated radiation therapy

Sponsor

European Organisation for Research and Treatment of Cancer - EORTC