Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease

NCT00719888 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

135

Enrollment

OTHER

Sponsor class

Conditions

Acute Biphenotypic Leukemia
Acute Lymphoblastic Leukemia
Acute Myeloid Leukemia
Burkitt Lymphoma
Chronic Lymphocytic Leukemia
Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Follicular Lymphoma
Lymphoblastic Lymphoma
Lymphoplasmacytic Lymphoma
Mantle Cell Lymphoma
Marginal Zone Lymphoma
Myelodysplastic Syndrome
Myelofibrosis
Non-Hodgkin Lymphoma
Plasma Cell Myeloma
Prolymphocytic Leukemia
Refractory Anemia
Small Lymphocytic Lymphoma

Interventions

DRUG: Cyclophosphamide
DRUG: Cyclosporine
PROCEDURE: Double-Unit Umbilical Cord Blood Transplantation
DRUG: Fludarabine
OTHER: Laboratory Biomarker Analysis
DRUG: Mycophenolate Mofetil
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation
DRUG: Thiotepa

Sponsor

Fred Hutchinson Cancer Center