Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment
Stopped Protocol objective could not be met. A new study with amended eligibility criteria will be developed.
Conditions
- Chronic Myeloproliferative Disorders
- Leukemia
- Lymphoma
- Multiple Myeloma and Plasma Cell Neoplasm
- Myelodysplastic Syndromes
- Myelodysplastic/Myeloproliferative Neoplasms
Interventions
- DRUG: fludarabine phosphate
- DRUG: melphalan
- PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation
- RADIATION: intensity-modulated radiation therapy
- RADIATION: tomotherapy
- RADIATION: total marrow irradiation
- RADIATION: total nodal irradiation
Sponsor
City of Hope Medical Center
Collaborators