Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

NCT00873275 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

11

Enrollment

OTHER

Sponsor class

Conditions

Colorectal Cancer

Interventions

BIOLOGICAL: bevacizumab
DRUG: FOLFOX regimen
DRUG: fluorouracil
DRUG: leucovorin calcium
DRUG: oxaliplatin
DRUG: ursodiol
GENETIC: RNA analysis
GENETIC: gene expression analysis
GENETIC: polymerase chain reaction
GENETIC: western blotting
OTHER: immunohistochemistry staining method
OTHER: laboratory biomarker analysis
OTHER: pharmacological study
PROCEDURE: positron emission tomography (PET)

Sponsor

City of Hope Medical Center

Collaborators

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