A Comparative Bioavailability/Food Effect Study of Immediate-Release and Extended-Release Tramadol HCl/Acetaminophen Combination Products Following Single-Dose and Multiple-Dose Administration in Healthy Adult Volunteers

PHASE1

Phase

COMPLETED

Status

Enrollment

INDUSTRY

Sponsor class

Conditions

DRUG: DDS-06C (650 mg acetaminophen and 75 mg tramadol HCl)
DRUG: DDS-06C (650 mg acetaminophen and 75 mg tramadol)
DRUG: Zaldiar®
DRUG: Ultracet®
DRUG: Two tablets of DDS-06C (650 mg acetaminophen and 75 mg tramadol HCl), multiple doses, under both fed and fasting conditions
DRUG: Zaldiar®, multiple doses,(fed & fasting):
DRUG: Ultracet®, multiple doses, (fed & fasting)

Labopharm Inc.