Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

Conditions

• Leukemia
• Mucositis
• Oral Complications

Interventions

• BIOLOGICAL: palifermin
• BIOLOGICAL: rituximab
• DRUG: cyclophosphamide
• DRUG: cytarabine
• DRUG: daunorubicin hydrochloride
• DRUG: etoposide
• DRUG: fludarabine phosphate
• DRUG: imatinib mesylate
• DRUG: melphalan
• DRUG: mercaptopurine
• DRUG: methotrexate
• DRUG: nelarabine
• DRUG: pegaspargase
• DRUG: vincristine sulfate
• PROCEDURE: allogeneic hematopoietic stem cell transplantation
• RADIATION: total-body irradiation

Sponsor

University College, London