Study of Different Formulations of a Clostridium Difficile Toxoid Vaccine Given at Three Different Schedules in Adults

Conditions

• Clostridium Difficile Infection
• Diarrhea

Interventions

• BIOLOGICAL: Clostridium difficile toxoids A and B (Low-dose with adjuvant)
• BIOLOGICAL: Clostridium difficile toxoids A and B (Low-dose without adjuvant)
• BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)
• BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose without adjuvant)
• BIOLOGICAL: Placebo: 0.9% normal saline
• BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)
• BIOLOGICAL: Clostridium difficile toxoids A and B (high-dose with adjuvant)

Sponsor

Sanofi Pasteur, a Sanofi Company