Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps

NCT01350258 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

TERMINATED

Status

8

Enrollment

OTHER

Sponsor class

Stopped Poor accrual

Conditions

Hematologic Malignancies
Acute Leukemia
Myelodysplastic Syndromes (MDS) Other Than RA or RARS Subtypes
Hodgkin's Lymphoma
Non-Hodgkin's Lymphoma
Myeloma
Chronic Myelogenous (or Myeloid) Leukemia (CML) Resistant to STI Therapy

Interventions

DRUG: Fludarabine
DRUG: Thiotepa
RADIATION: Total Body Irradiation (TBI)
BIOLOGICAL: Donor Lymphocyte Infusion (DLI)
DRUG: Melphalan
DEVICE: Hematopoietic stem cell transplantation (HSCT)

Sponsor

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University