High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

NCT01378481 · clinicaltrials.gov ↗

PHASE1

Phase

TERMINATED

Status

30

Enrollment

NIH

Sponsor class

Conditions

Adult Anaplastic Astrocytoma
Adult Anaplastic Oligodendroglioma
Adult Giant Cell Glioblastoma
Adult Glioblastoma
Adult Gliosarcoma
Adult Mixed Glioma
Recurrent Adult Brain Neoplasm

Interventions

DRUG: Vorinostat
RADIATION: Stereotactic Radiosurgery
OTHER: Laboratory Biomarker Analysis
OTHER: Pharmacological Study
PROCEDURE: Therapeutic Conventional Surgery

Sponsor

National Cancer Institute (NCI)