Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma
Stopped No participants enrolled.
Conditions
- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
- Ewing Sarcoma of Bone
- Extraosseous Ewing Sarcoma
- Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
- Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Interventions
- DRUG: etoposide
- DRUG: ifosfamide
- RADIATION: intensity-modulated radiation therapy
- DRUG: topotecan hydrochloride
- DRUG: busulfan
- DRUG: melphalan
- PROCEDURE: autologous hematopoietic stem cell transplantation
- PROCEDURE: peripheral blood stem cell transplantation
- PROCEDURE: autologous bone marrow transplantation
Sponsor
City of Hope Medical Center
Collaborators