Inhalational Anesthesia and Precipitation of Dementia: is There a Link?

NCT01903421 · clinicaltrials.gov ↗

NA

Phase

UNKNOWN

Status

500

Enrollment

OTHER

Sponsor class

Conditions

Alzheimer's Disease
Dementia

Interventions

DRUG: Spinal anesthesia group: bupivacaine 10-15mg
DRUG: General anesthesia group: induction propofol 1.5-2mg/kg and fentanyl 1-3g/kg, maintained with isoflurane or sevoflurane
GENETIC: Blood test
OTHER: Lumbar spinal tap
BEHAVIORAL: Montreal Cognitive Assessment (MOCA) and MMSE

Sponsor

University Health Network, Toronto