Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS

Conditions

• Polycystic Ovary Syndrome
• Infertility

Interventions

• DRUG: induction of ovulation using letrozole-pioglitazone-metformin
• DRUG: induction of ovulation using clomiphene citrate-pioglitazone-metformin
• RADIATION: transvaginal ultrasound
• OTHER: body mass index (BMI) calculation
• OTHER: day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone
• OTHER: pretreatment blood urea and serum creatinine
• OTHER: serum estradiol (E2) on day 12
• OTHER: serum progesterone on day 21
• OTHER: blood urea and serum creatinine every month

Sponsor

Cairo University