Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

NCT01922076 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

46

Enrollment

NIH

Sponsor class

Conditions

Anaplastic Astrocytoma
Anaplastic Oligoastrocytoma
Diffuse Intrinsic Pontine Glioma
Diffuse Midline Glioma, H3 K27M-Mutant
Glioblastoma
Gliosarcoma

Interventions

DRUG: Adavosertib
OTHER: Laboratory Biomarker Analysis
OTHER: Pharmacological Study
RADIATION: Radiation Therapy

Sponsor

National Cancer Institute (NCI)