Efficacy Study of Different Laboratory Management Strategies and Drug Regimens in HIV-infected Children in Africa

NCT02028676 · clinicaltrials.gov ↗

PHASE4

Phase

COMPLETED

Status

1206

Enrollment

OTHER_GOV

Sponsor class

Conditions

Human Immunodeficiency Virus

Interventions

OTHER: Clinically Driven Monitoring (CDM)
OTHER: Laboratory plus Clinical Monitoring (LCM)
DRUG: Arm A: ABC+3TC+NNRTI
DRUG: Arm B: ZDV+ABC+3TC+NNRTI->ABC+3TC+NNRTI maintenance
DRUG: Arm C: ZDV+ABC+3TC+NNRTI->ZDV+ABC+3TC maintenance
DRUG: Once-daily ABC+3TC
DRUG: Twice-daily ABC+3TC
DRUG: Continued cotrimoxazole prophylaxis
OTHER: Stopped cotrimoxazole prophylaxis

Sponsor

Medical Research Council

Collaborators

[object Object]
[object Object]
[object Object]