International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Conditions

• Brain Tumors

Interventions

• RADIATION: Radiotherapy without Carboplatin
• DRUG: Reduced-intensity maintenance chemotherapy
• RADIATION: Radiotherapy with Carboplatin
• DRUG: Maintenance chemotherapy
• RADIATION: WNT-HR < 16 years
• RADIATION: WNT-HR >= 16 years
• DRUG: Induction Chemotherapy
• RADIATION: SHH-TP53 M0
• RADIATION: SHH-TP53 M+ (germline)
• RADIATION: SHH-TP53 (somatic)
• DRUG: Vinblastin Maintenance

Sponsor

Universitätsklinikum Hamburg-Eppendorf

Collaborators

• Deutsche Kinderkrebsstiftung