C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer
Stopped The study did not open to accrual. No start date and no completion dates.
Conditions
- Adenocarcinoma of the Esophagus
- Adenocarcinoma of the Gastroesophageal Junction
- Diffuse Adenocarcinoma of the Stomach
- Gastrointestinal Cancer
- Intestinal Adenocarcinoma of the Stomach
- Mixed Adenocarcinoma of the Stomach
- Stage IIIA Esophageal Cancer
- Stage IIIA Gastric Cancer
- Stage IIIB Esophageal Cancer
- Stage IIIB Gastric Cancer
- Stage IIIC Esophageal Cancer
- Stage IIIC Gastric Cancer
- Stage IV Esophageal Cancer
- Stage IV Gastric Cancer
Interventions
- DRUG: c-Met inhibitor AMG 337
- OTHER: placebo
- DRUG: oxaliplatin
- DRUG: leucovorin calcium
- DRUG: fluorouracil
- OTHER: pharmacological study
- OTHER: laboratory biomarker analysis
Sponsor
Eastern Cooperative Oncology Group
Collaborators
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