L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury

NCT02664753 · clinicaltrials.gov ↗

PHASE3

Phase

TERMINATED

Status

254

Enrollment

OTHER

Sponsor class

Stopped Exposure to serious adverse events related to the research (i.e., death), the mnts = 54% versus 58 deaths out of 121 patients = 48%).onitoring committee unanimously recommended discontinuation of the trial.

Conditions

Severe Sepsis
Shock, Septic
Acute Kidney Injury

Interventions

DRUG: 56 days of weight-adjusted L-Carnitine treatment
DRUG: 10 days of intravenous placebo (isotonic saline)

Sponsor

Centre Hospitalier Universitaire de Nīmes