Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Conditions

• Deleterious BARD1 Gene Mutation
• Deleterious BRCA1 Gene Mutation
• Deleterious BRCA2 Gene Mutation
• Deleterious BRIP1 Gene Mutation
• Deleterious EPCAM Gene Mutation
• Deleterious MLH1 Gene Mutation
• Deleterious MSH2 Gene Mutation
• Deleterious MSH6 Gene Mutation
• Deleterious PALB2 Gene Mutation
• Deleterious PMS2 Gene Mutation
• Deleterious RAD51C Gene Mutation
• Deleterious RAD51D Gene Mutation
• Hereditary Breast and Ovarian Cancer Syndrome
• Premenopausal

Interventions

• OTHER: Laboratory Biomarker Analysis
• PROCEDURE: Oophorectomy
• OTHER: Quality-of-Life Assessment
• PROCEDURE: Salpingectomy
• PROCEDURE: Salpingo-Oophorectomy

Sponsor

M.D. Anderson Cancer Center

Collaborators

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