The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4

Conditions

• Hereditary Spastic Paraplegia
• Hereditary, Spastic Paraplegia, Autosomal Dominant

Interventions

• OTHER: SPRS Score and clinical signs
• BEHAVIORAL: Cognition Testing using CANTAB
• DIAGNOSTIC_TEST: Lumbar Puncture and blood draw
• DIAGNOSTIC_TEST: MRI
• DIAGNOSTIC_TEST: Electrophysiology
• DIAGNOSTIC_TEST: Testing functional performance
• DIAGNOSTIC_TEST: Non motor symptoms

Sponsor

University Hospital Tuebingen