Phase I Study of APX005M in Pediatric Central Nervous System Tumors

NCT03389802 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

32

Enrollment

NETWORK

Sponsor class

Conditions

Glioblastoma Multiforme
High-grade Astrocytoma Not Otherwise Specified (NOS)
CNS Primary Tumor, Not Otherwise Specified (NOS)
Ependymoma, Not Otherwise Specified (NOS)
Diffuse Intrinsic Pontine Gliomas (DIPG)
Medulloblastoma

Interventions

BIOLOGICAL: APX005M treatment for recurrent or refractory primary malignant CNS tumor patients
BIOLOGICAL: APX005M treatment for newly diagnosed DIPG patients

Sponsor

Pediatric Brain Tumor Consortium

Collaborators

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