Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

Phase

TERMINATED

Status

175

Enrollment

OTHER

Sponsor class

Stopped Terminated 9/24/23 at 85% target enrollment due to slow accrual of subjects. The decline in enrollment was attributed to changing surgical demographics (higher MELD, more DCD grafts, and increasing use of Normothermic Perfusion technology).

Conditions

Cirrhosis
End Stage Liver Disease
Acute Kidney Injury
Liver Transplant; Complications
Chronic Kidney Diseases
Hepatitis c
Hepatitis B
NASH - Nonalcoholic Steatohepatitis
Alcoholic Cirrhosis
Hepatocellular Carcinoma

Interventions

DEVICE: Esophageal cooling/warming device
OTHER: Mild hypothermia
OTHER: Normothermia

Sponsor

University of California, San Francisco

Collaborators

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