Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)"

Conditions

• HPV Related Oropharyngeal Squamous Cell Carcinoma

Interventions

• DRUG: Cisplatin
• RADIATION: Intensity modulated radiation therapy
• RADIATION: Intensity modulated proton therapy
• PROCEDURE: Surgery
• OTHER: FACT-H&N
• OTHER: MD Anderson Dysphagia Inventory
• OTHER: University of Michigan Xerostomia Index
• OTHER: Scale of Subjective Total Taste Acuity
• OTHER: Neck Dissection Impairment Index

Sponsor

Washington University School of Medicine