A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

NCT03914625 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

6720

Enrollment

NIH

Sponsor class

Conditions

B Acute Lymphoblastic Leukemia
B Lymphoblastic Lymphoma
Down Syndrome

Interventions

DRUG: Asparaginase Erwinia chrysanthemi
BIOLOGICAL: Blinatumomab
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dexamethasone
DRUG: Doxorubicin Hydrochloride
DRUG: Leucovorin Calcium
DRUG: Mercaptopurine
DRUG: Mercaptopurine Oral Suspension
DRUG: Methotrexate
DRUG: Pegaspargase
DRUG: Prednisolone
DRUG: Prednisone
RADIATION: Radiation Therapy
RADIATION: Radiation Therapy
DRUG: Thioguanine
DRUG: Vincristine Sulfate

Sponsor

National Cancer Institute (NCI)