Stem Cell Transplantation in Crohn's Disease

NCT04224558 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

RECRUITING

Status

15

Enrollment

OTHER

Sponsor class

Conditions

Crohn Disease

Interventions

DRUG: Mesna
DRUG: Cyclophosphamide
DRUG: Filgrastim
PROCEDURE: Apheresis catheter placement
PROCEDURE: Leukapheresis
DRUG: Fludarabine
DRUG: Methylprednisolone
DRUG: Diphenhydramine
DRUG: Acetaminophen
DRUG: anti-thymocyte globulin (rabbit)
DRUG: lymphocyte immune globulin
BIOLOGICAL: Peripheral Blood Stem Cell Infusion
DRUG: Cytoxan

Sponsor

Cedars-Sinai Medical Center