Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer

NCT04329065 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

25

Enrollment

OTHER

Sponsor class

Conditions

Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8

Interventions

BIOLOGICAL: pUMVC3-IGFBP2-HER2-IGF1R Plasmid DNA Vaccine
DRUG: Paclitaxel
BIOLOGICAL: Trastuzumab
BIOLOGICAL: Pertuzumab
DRUG: Docetaxel
DRUG: Carboplatin
PROCEDURE: Ultrasound Imaging
PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection

Sponsor

University of Washington

Collaborators

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