A Pilot Trial to Determine the Effective N-acetylcysteine Dose for Opioid Reduction for Spine Surgery.

NCT04562597 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

50

Enrollment

OTHER

Sponsor class

Conditions

Surgery

Interventions

DRUG: Dose Response Curve Placebo
DRUG: Dose Response Curve N-acetylcysteine 50 mg/kg
DRUG: Dose Response Curve N-acetylcysteine 100 mg/kg
DRUG: Dose Response Curve N-acetylcysteine 150 mg/kg
DRUG: Opioid Reduction with Optimal N-acetylcysteine Dose
DRUG: Placebo

Sponsor

Medical University of South Carolina