A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

NCT04573140 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

28

Enrollment

OTHER

Sponsor class

Conditions

Adult Glioblastoma
High Grade Glioma
WHO Grade III or IV Malignant Glioma

Interventions

BIOLOGICAL: Autologous total tumor mRNA and pp65 full length (fl) lysosomal associated membrane protein (LAMP) mRNA loaded DOTAP liposome vaccine administered intravenously (RNA loaded lipid particles, RNA-LPs)

Sponsor

University of Florida

Collaborators

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