Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
Stopped Inadequate accrual rate
Conditions
- Anatomic Stage IV Breast Cancer AJCC v8
- Metastatic Lung Non-Small Cell Carcinoma
- Metastatic Lung Small Cell Carcinoma
- Metastatic Malignant Breast Neoplasm
- Metastatic Malignant Digestive System Neoplasm
- Metastatic Malignant Neoplasm in the Brain
- Metastatic Malignant Solid Neoplasm
- Metastatic Melanoma
- Metastatic Renal Cell Carcinoma
- Recurrent Brain Neoplasm
- Stage IV Lung Cancer AJCC v8
- Stage IV Renal Cell Cancer AJCC v8
Interventions
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Computed Tomography
- PROCEDURE: Magnetic Resonance Imaging
- DRUG: Memantine
- OTHER: Quality-of-Life Assessment
- OTHER: Questionnaire Administration
- RADIATION: Stereotactic Radiosurgery
- RADIATION: Whole-Brain Radiotherapy
Sponsor
NRG Oncology
Collaborators