A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy Subjects

NCT04798209 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

70

Enrollment

INDUSTRY

Sponsor class

Conditions

Healthy

Interventions

DRUG: ACT-777991 (SAD)
DRUG: ACT-777991 (MAD)
DRUG: Placebo (SAD)
DRUG: Placebo (MAD)
DRUG: 14C-ACT-777991 microtracer (SAD - Absolute Bioavailability)
DRUG: Microtracer matching placebo (SAD - Absolute Bioavailability)
DRUG: 14C-ACT-777991 microtracer (MAD - ADME)
DRUG: Microtracer matching placebo (MAD - ADME)

Sponsor

Idorsia Pharmaceuticals Ltd.