Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Conditions
- Metastatic Lung Small Cell Carcinoma
- Metastatic Malignant Neoplasm in the Brain
- Recurrent Lung Small Cell Carcinoma
- Stage IV Lung Cancer AJCC v8
Interventions
- PROCEDURE: Biospecimen Collection
- PROCEDURE: Magnetic Resonance Imaging
- DRUG: Memantine Hydrochloride
- OTHER: Neurocognitive Assessment
- RADIATION: Stereotactic Radiosurgery
- OTHER: Survey Administration
- RADIATION: Whole-Brain Radiotherapy
Sponsor
NRG Oncology
Collaborators