Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

NCT04898894 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

37

Enrollment

OTHER

Sponsor class

Conditions

Acute Leukemia of Ambiguous Lineage in Relapse
Acute Myeloid Leukemia, in Relapse
Refractory Acute Leukemia of Ambiguous Lineage
Refractory Acute Myeloid Leukemia

Interventions

DRUG: Venetoclax
DRUG: Selinexor
DRUG: Cytarabine
DRUG: Fludarabine
BIOLOGICAL: Filgrastim
DRUG: Methotrexate
DRUG: methotrexate/hydrocortisone/cytarabine

Sponsor

St. Jude Children's Research Hospital

Collaborators

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