HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
ACTIVE_NOT_RECRUITING
Status
Conditions
- Acute Lymphoblastic Leukemia
- Acute Myelogenous Leukemia
- Mixed Phenotype Acute Leukemia
- Acute Leukemia
- Myelodysplastic Syndromes
- Chronic Myelogenous Leukemia
- Chronic Lymphocytic Leukemia
- Lymphoma
Interventions
- DRUG: Busulfan
- DRUG: Busulfan
- DRUG: Fludarabine
- RADIATION: Total-body irradiation
- DRUG: Cyclophosphamide
- DRUG: Melphalan
- PROCEDURE: PBSC Hematopoietic Stem Cell Transplantation (HSCT)
- PROCEDURE: Bone Marrow Hematopoietic Stem Cell Transplantation
- DRUG: Post-transplant Cyclophosphamide
- DRUG: Mesna
- DRUG: Tacrolimus
- DRUG: Mycophenolate Mofetil
- OTHER: Patient-Reported Outcomes
Sponsor
Center for International Blood and Marrow Transplant Research
Collaborators