Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer
Conditions
- Locally Advanced Lung Non-Small Cell Carcinoma
- Stage II Lung Cancer AJCC v8
- Stage IIA Lung Cancer AJCC v8
- Stage IIB Lung Cancer AJCC v8
- Stage III Lung Cancer AJCC v8
- Stage IIIA Lung Cancer AJCC v8
- Stage IIIB Lung Cancer AJCC v8
- Stage IIIC Lung Cancer AJCC v8
- Unresectable Lung Non-Small Cell Carcinoma
Interventions
- DRUG: Carboplatin
- BIOLOGICAL: Durvalumab
- DRUG: Paclitaxel
- DRUG: Papaverine
- RADIATION: Radiation Therapy
- DRUG: Pemetrexed
- RADIATION: Hypofractionated Radiation Therapy
- PROCEDURE: Magnetic Resonance Imaging
- PROCEDURE: Positron Emission Tomography
- PROCEDURE: Computed Tomography
- PROCEDURE: Magnetic Resonance Imaging of the Brain with and without Contrast
- PROCEDURE: Biospecimen Collection
Sponsor
Ohio State University Comprehensive Cancer Center
Collaborators