SMMART Adaptive Clinical Treatment (ACT) Trial

NCT05238831 · clinicaltrials.gov ↗

EARLY_PHASE1

Phase

WITHDRAWN

Status

OTHER

Sponsor class

Stopped Withdrawn due to a change in therapeutic interventions.

Conditions

Advanced Breast Carcinoma
Advanced Malignant Solid Neoplasm
Advanced Ovarian Carcinoma
Advanced Pancreatic Carcinoma
Advanced Prostate Carcinoma
Advanced Sarcoma
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Recurrent Adult Soft Tissue Sarcoma
Recurrent Breast Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Prostate Carcinoma
Stage II Pancreatic Cancer AJCC v8
Stage III Ovarian Cancer AJCC v8
Stage III Pancreatic Cancer AJCC v8
Stage IV Ovarian Cancer AJCC v8
Stage IV Pancreatic Cancer AJCC v8

Interventions

DRUG: Alectinib
DRUG: Alpelisib
DRUG: Anastrozole
BIOLOGICAL: Atezolizumab
BIOLOGICAL: Bevacizumab
PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
DRUG: Capecitabine
DRUG: Carboplatin
DRUG: Cobimetinib
DRUG: Entrectinib
DRUG: Eribulin
DRUG: Fulvestrant
BIOLOGICAL: Hyaluronidase-zzxf/Pertuzumab/Trastuzumab
DRUG: Irinotecan
DRUG: Letrozole
DRUG: Nab-paclitaxel
DRUG: Niraparib
DRUG: Olaparib
DRUG: Paclitaxel

Sponsor

OHSU Knight Cancer Institute

Collaborators

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