A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

NCT05307939 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

30

Enrollment

OTHER

Sponsor class

Conditions

HPV
Oropharynx Cancer
HPV-Related Carcinoma
HPV-Related Malignancy
HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions

DIAGNOSTIC_TEST: HPV ctDNA Assay
DIAGNOSTIC_TEST: MRI Studies
BEHAVIORAL: EORTC QLQ H&N 35 and C30
BEHAVIORAL: MDADI-HN
BEHAVIORAL: COST-FACIT
RADIATION: Intensity-Modulated Radiation Therapy (Arm A)
COMBINATION_PRODUCT: Chemoradiation (Arm B)

Sponsor

Memorial Sloan Kettering Cancer Center