Subclinical Hypothyroidism and Chronic Inflammation in PCOS

Conditions

• PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
• Subclinical hypothyroïdism
• Hypothalamic-Pituitary-Gonadal Axis Dysfunction

Interventions

• DIAGNOSTIC_TEST: Measurement and comparison of leucocytosis and concentrations of CRP, procalcitonin, fibrinogen, ferritin, IL-1, IL-6, IL-10, TNF-alpha in both study arms
• DIAGNOSTIC_TEST: Evaluation of the impact of subclinical hypothyroidism, with present/ absent antithyroid antibodies, on the balance between anti- and pro-inflammatory factors in women in both study arms
• DIAGNOSTIC_TEST: Assessment of the impact of imbalance between anti- and pro-inflammatory factors in women with different PCOS and HPOD phenotypes on ovarian reserve indices

Sponsor

Jagiellonian University